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Target
Dual specificity protein phosphatase 3
Ligand
BDBM88750
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
1420±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM88750
Synonyms:
(4-ethoxyphenyl)-(4-methyl-1-piperazinyl)methanethione | (4-ethoxyphenyl)-(4-methylpiperazin-1-yl)methanethione | (4-methylpiperazino)-p-phenetyl-methanethione | 1-[(4-ethoxyphenyl)carbonothioyl]-4-methylpiperazine | MLS000663479 | SMR000292624 | cid_892521
Type:
Small organic molecule
Emp. Form.:
C14H20N2OS
Mol. Mass.:
264.386
SMILES:
CCOc1ccc(cc1)C(=S)N1CCN(C)CC1
Structure:
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