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Target
Dual specificity protein phosphatase 3
Ligand
BDBM88777
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
25400±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM88777
Synonyms:
4-[5-(2,5-dichlorophenyl)-1,2,4-oxadiazol-3-yl]pyridine | 5-(2,5-dichlorophenyl)-3-(4-pyridyl)-1,2,4-oxadiazole | 5-(2,5-dichlorophenyl)-3-pyridin-4-yl-1,2,4-oxadiazole | 5-[2,5-bis(chloranyl)phenyl]-3-pyridin-4-yl-1,2,4-oxadiazole | MLS001000871 | SMR000497742 | cid_895032
Type:
Small organic molecule
Emp. Form.:
C13H7Cl2N3O
Mol. Mass.:
292.12
SMILES:
Clc1ccc(Cl)c(c1)-c1nc(no1)-c1ccncc1
Structure:
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