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Target
Dual specificity protein phosphatase 3
Ligand
BDBM88787
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
1930±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM88787
Synonyms:
(2Z)-2-(salicyloylhydrazono)chromene-3-carboxamide | (2Z)-2-[(2-hydroxybenzoyl)hydrazinylidene]chromene-3-carboxamide | (2Z)-2-[(2-hydroxybenzoyl)hydrazono]-2H-chromene-3-carboxamide | (2Z)-2-[(2-hydroxyphenyl)carbonylhydrazinylidene]chromene-3-carboxamide | (2Z)-2-[[(2-hydroxyphenyl)-oxomethyl]hydrazinylidene]-1-benzopyran-3-carboxamide | MLS001194671 | SMR000554966 | cid_9629545
Type:
Small organic molecule
Emp. Form.:
C17H13N3O4
Mol. Mass.:
323.3028
SMILES:
NC(=O)c1cc2ccccc2o\c1=N/NC(=O)c1ccccc1O
Structure:
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