Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 3
Ligand
BDBM88795
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
26800±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM88795
Synonyms:
2-[[2-(4-methoxyphenyl)-5-methyl-oxazol-4-yl]methylsulfonyl]-N-(2-p-phenetylethyl)acetamide | MLS000923912 | N-[2-(4-ethoxyphenyl)ethyl]-2-[[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfonyl]acetamide | N-[2-(4-ethoxyphenyl)ethyl]-2-[[2-(4-methoxyphenyl)-5-methyl-1,3-oxazol-4-yl]methylsulfonyl]ethanamide | N-[2-(4-ethoxyphenyl)ethyl]-2-[[2-(4-methoxyphenyl)-5-methyl-4-oxazolyl]methylsulfonyl]acetamide | SMR000623322 | cid_16008051
Type:
Small organic molecule
Emp. Form.:
C24H28N2O6S
Mol. Mass.:
472.554
SMILES:
CCOc1ccc(CCNC(=O)CS(=O)(=O)Cc2nc(oc2C)-c2ccc(OC)cc2)cc1
Structure:
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