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Target
Dual specificity protein phosphatase 3
Ligand
BDBM88802
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
1550±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM88802
Synonyms:
MLS001229931 | N-[(E)-3-furanylmethylideneamino]-3,5-dihydroxybenzamide | N-[(E)-3-furfurylideneamino]-3,5-dihydroxy-benzamide | N-[(E)-furan-3-ylmethylideneamino]-3,5-bis(oxidanyl)benzamide | N-[(E)-furan-3-ylmethylideneamino]-3,5-dihydroxybenzamide | SMR000678825 | cid_25237581
Type:
Small organic molecule
Emp. Form.:
C12H10N2O4
Mol. Mass.:
246.2188
SMILES:
Oc1cc(O)cc(c1)C(=O)N\N=C\c1ccoc1
Structure:
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