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Target
Dual specificity protein phosphatase 3
Ligand
BDBM88804
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
1320±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM88804
Synonyms:
2-(2,3-dihydro-1H-inden-5-yl)-N-[2-(2-methoxyanilino)-2-oxoethyl]-N-propylacetamide | 2-(2,3-dihydro-1H-inden-5-yl)-N-[2-[(2-methoxyphenyl)amino]-2-oxidanylidene-ethyl]-N-propyl-ethanamide | 2-indan-5-yl-N-[2-keto-2-(o-anisidino)ethyl]-N-propyl-acetamide | MLS002182836 | SMR001271866 | cid_25161958
Type:
Small organic molecule
Emp. Form.:
C23H28N2O3
Mol. Mass.:
380.48
SMILES:
CCCN(CC(=O)Nc1ccccc1OC)C(=O)Cc1ccc2CCCc2c1
Structure:
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