Target
Dual specificity protein phosphatase 3
Ligand
BDBM88807
Substrate
n/a
Meas. Tech.
Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay
IC50
4050±n/a nM
Citation
 PubChem, PC Dose Response selectivity of inhibitors of STriatal-Enriched Phosphatase (STEP) in the dual-specificity protein-tyrosine phosphatase VHR Inhibition Assay PubChem Bioassay (2012)[AID] 
Target
Name:
Dual specificity protein phosphatase 3
Synonyms:
DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR
Type:
Hydrolase
Mol. Mass.:
20480.58
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
185
Sequence:
MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVLNAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRVLVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKEGKLKP
  
Inhibitor
Name:
BDBM88807
Synonyms:
1,3-bis[[(E)-(6-ketocyclohexa-2,4-dien-1-ylidene)methyl]amino]urea | 1,3-bis[[(E)-(6-oxidanylidenecyclohexa-2,4-dien-1-ylidene)methyl]amino]urea | 1,3-bis[[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]amino]urea | 1,3-bis[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]urea | MLS002667171 | SMR001556943 | cid_5372293
Type:
Small organic molecule
Emp. Form.:
C15H14N4O3
Mol. Mass.:
298.2967
SMILES:
Oc1ccccc1C=NNC(=O)NN=Cc1ccccc1O |w:8.9,13.13|
Structure:
Search PDB for entries with ligand similarity: