Target
Mitochondrial import inner membrane translocase subunit TIM23
Ligand
BDBM89047
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1 yeast via a luminescent assay
IC50
787±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1 yeast via a luminescent assay PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM23
Synonyms:
MAS6 | MIM23 | MPI3 | TIM23 | TIM23_YEAST | TPA: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23245.32
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285814664
Residue:
222
Sequence:
MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHPLAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQGLQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIGAGALTGALFKSSKGLKPMGYSSAMVAAACAVWCSVKKRLLEK
  
Inhibitor
Name:
BDBM89047
Synonyms:
MLS-0454717.0001 | [(Z)-[(4-bromophenyl)-morpholin-4-yl-methylidene]amino] benzoate | [(Z)-[(4-bromophenyl)-morpholin-4-ylmethylidene]amino] benzoate | benzoic acid [(Z)-[(4-bromophenyl)-(4-morpholinyl)methylidene]amino] ester | benzoic acid [(Z)-[(4-bromophenyl)-morpholino-methylene]amino] ester | cid_5337954
Type:
Small organic molecule
Emp. Form.:
C18H17BrN2O3
Mol. Mass.:
389.243
SMILES:
Brc1ccc(cc1)C(=N\OC(=O)c1ccccc1)\N1CCOCC1
Structure:
Search PDB for entries with ligand similarity: