Reaction Details Report a problem with these data
Target
High affinity choline transporter 1
Ligand
BDBM78579
Substrate
n/a
Meas. Tech.
Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC
EC50
14810±n/a nM
Citation
 PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay (2012)[AID] 
Target
Name:
High affinity choline transporter 1
Synonyms:
CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1
Type:
PROTEIN
Mol. Mass.:
63194.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1464247
Residue:
580
Sequence:
MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFKTLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM78579
Synonyms:
MLS000121357 | N-[1-(5-Bromo-2-pentyloxy-phenyl)-ethylidene]-N'-(4,5-dihydro-1H-imidazol-2-yl)-hydrazine | N-[1-(5-bromanyl-2-pentoxy-phenyl)ethylideneamino]-4,5-dihydro-1H-imidazol-2-amine | N-[1-(5-bromo-2-pentoxyphenyl)ethylideneamino]-4,5-dihydro-1H-imidazol-2-amine | SMR000118779 | [(E)-1-(2-amoxy-5-bromo-phenyl)ethylideneamino]-(2-imidazolin-2-yl)amine | [1-(2-amoxy-5-bromo-phenyl)ethylideneamino]-(2-imidazolin-2-yl)amine | cid_3104172
Type:
Small organic molecule
Emp. Form.:
C16H23BrN4O
Mol. Mass.:
367.284
SMILES:
CCCCCOc1ccc(Br)cc1C(C)=NNC1=NCCN1 |w:15.16,t:18|
Structure:
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