Reaction Details Report a problem with these data
Target
High affinity choline transporter 1
Ligand
BDBM89149
Substrate
n/a
Meas. Tech.
Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC
EC50
9440±n/a nM
Citation
 PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay (2012)[AID] 
Target
Name:
High affinity choline transporter 1
Synonyms:
CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1
Type:
PROTEIN
Mol. Mass.:
63194.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1464247
Residue:
580
Sequence:
MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFKTLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM89149
Synonyms:
3-chloranyl-N-[3-[4-[3-[(3-chlorophenyl)carbonylamino]propyl]piperazin-1-yl]propyl]benzamide | 3-chloro-N-[3-(4-{3-[(3-chlorobenzoyl)amino]propyl}-1-piperazinyl)propyl]benzamide | 3-chloro-N-[3-[4-[3-[(3-chlorobenzoyl)amino]propyl]piperazin-1-yl]propyl]benzamide | 3-chloro-N-[3-[4-[3-[(3-chlorobenzoyl)amino]propyl]piperazino]propyl]benzamide | 3-chloro-N-[3-[4-[3-[[(3-chlorophenyl)-oxomethyl]amino]propyl]-1-piperazinyl]propyl]benzamide | MLS000702040 | SMR000227298 | cid_4341864
Type:
Small organic molecule
Emp. Form.:
C24H30Cl2N4O2
Mol. Mass.:
477.427
SMILES:
Clc1cccc(c1)C(=O)NCCCN1CCN(CCCNC(=O)c2cccc(Cl)c2)CC1
Structure:
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