Reaction Details Report a problem with these data
Target
High affinity choline transporter 1
Ligand
BDBM89173
Substrate
n/a
Meas. Tech.
Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC
EC50
15010±n/a nM
Citation
 PubChem, PC Dose responses of compounds that activate the Choline Transporter (CHT) - 10 point CRC PubChem Bioassay (2012)[AID] 
Target
Name:
High affinity choline transporter 1
Synonyms:
CHT1 | High-affinity choline transporter | SC5A7_HUMAN | SLC5A7 | high affinity choline transporter 1
Type:
PROTEIN
Mol. Mass.:
63194.33
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1464247
Residue:
580
Sequence:
MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGYGLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVDMHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSWLDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMILPIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTKTVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFKTLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNKEAFLDVDSSPEGSGTEDNLQ
  
Inhibitor
Name:
BDBM89173
Synonyms:
2-(2-cyanophenyl)sulfanyl-N-[(3-fluorophenyl)methyl]-N-methyl-benzamide | 2-(2-cyanophenyl)sulfanyl-N-[(3-fluorophenyl)methyl]-N-methylbenzamide | 2-[(2-cyanophenyl)thio]-N-(3-fluorobenzyl)-N-methyl-benzamide | 2-[(2-cyanophenyl)thio]-N-[(3-fluorophenyl)methyl]-N-methylbenzamide | MLS001150002 | SMR000688892 | cid_24818402
Type:
Small organic molecule
Emp. Form.:
C22H17FN2OS
Mol. Mass.:
376.447
SMILES:
CN(Cc1cccc(F)c1)C(=O)c1ccccc1Sc1ccccc1C#N
Structure:
Search PDB for entries with ligand similarity: