Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM77775
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen.
IC50
>99000±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM77775
Synonyms:
MLS000712057 | N-(4-imidazo[1,2-a]pyridin-2-ylphenyl)thiophene-2-carboxamide | N-[4-(2-imidazo[1,2-a]pyridinyl)phenyl]-2-thiophenecarboxamide | SMR000281824 | cid_695176
Type:
Small organic molecule
Emp. Form.:
C18H13N3OS
Mol. Mass.:
319.38
SMILES:
O=C(Nc1ccc(cc1)-c1cn2ccccc2n1)c1cccs1
Structure:
Search PDB for entries with ligand similarity: