Target
Mitochondrial import inner membrane translocase subunit TIM10
Ligand
BDBM89130
Substrate
n/a
Meas. Tech.
SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen.
IC50
82620±n/a nM
Citation
 PubChem, PC SAR analysis of small molecule inhibitors of tim23-1: a luminescent TIM10 yeast counterscreen. PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial import inner membrane translocase subunit TIM10
Synonyms:
MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...
Type:
Enzyme Catalytic Domain
Mol. Mass.:
10303.50
Organism:
Saccharomyces cerevisiae S288c
Description:
gi_285809906
Residue:
93
Sequence:
MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESSCLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
  
Inhibitor
Name:
BDBM89130
Synonyms:
2-(4-mesylpiperazino)-6-methyl-1H-benzimidazole | 6-methyl-2-(4-methylsulfonyl-1-piperazinyl)-1H-benzimidazole | 6-methyl-2-(4-methylsulfonylpiperazin-1-yl)-1H-benzimidazole | MLS-0463408.0001 | cid_45497244
Type:
Small organic molecule
Emp. Form.:
C13H18N4O2S
Mol. Mass.:
294.373
SMILES:
Cc1ccc2nc([nH]c2c1)N1CCN(CC1)S(C)(=O)=O
Structure:
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