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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM89528
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM89528
Synonyms:
2-(4-Ethoxy-3,5-dimethyl-phenyl)-pyridin-3-ol | 2-(4-ethoxy-3,5-dimethyl-phenyl)pyridin-3-ol;hydrochloride | 2-(4-ethoxy-3,5-dimethylphenyl)-3-pyridinol;hydrochloride | 2-(4-ethoxy-3,5-dimethylphenyl)pyridin-3-ol;hydrochloride | MLS000030921 | SMR000010527 | cid_6603361
Type:
Small organic molecule
Emp. Form.:
C15H17NO2
Mol. Mass.:
243.301
SMILES:
CCOc1c(C)cc(cc1C)-c1ncccc1O
Structure:
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