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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM89570
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
22600±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM89570
Synonyms:
2-(2-ethyl-1-piperidinyl)-1-(2-methyl-1H-indol-3-yl)ethanone | 2-(2-ethylpiperidin-1-yl)-1-(2-methyl-1H-indol-3-yl)ethanone | 2-(2-ethylpiperidino)-1-(2-methyl-1H-indol-3-yl)ethanone | MLS000037417 | SMR000040265 | cid_659344
Type:
Small organic molecule
Emp. Form.:
C18H24N2O
Mol. Mass.:
284.396
SMILES:
CCC1CCCCN1CC(=O)c1c(C)[nH]c2ccccc12
Structure:
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