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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM89640
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID]
More Info.:
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
Inhibitor
Name:
BDBM89640
Synonyms:
3-(2,5,6-trimethyl-1-benzimidazolyl)-1-propanamine;hydrochloride | 3-(2,5,6-trimethyl-1H-benzimidazol-1-yl)propan-1-amine | 3-(2,5,6-trimethylbenzimidazol-1-yl)propan-1-amine;hydrochloride | 3-(2,5,6-trimethylbenzimidazol-1-yl)propylamine;hydrochloride | MLS000048028 | SMR000048853 | cid_6603308
Type:
Small organic molecule
Emp. Form.:
C13H19N3
Mol. Mass.:
217.3101
SMILES:
Cc1nc2cc(C)c(C)cc2n1CCCN