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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM89675
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM89675
Synonyms:
MLS000046580 | N-(3-isopropoxypropyl)-1-(propylsulfonyl)piperidine-4-carboxamide | N-(3-isopropoxypropyl)-1-propylsulfonyl-isonipecotamide | N-(3-propan-2-yloxypropyl)-1-propylsulfonyl-4-piperidinecarboxamide | N-(3-propan-2-yloxypropyl)-1-propylsulfonyl-piperidine-4-carboxamide | N-(3-propan-2-yloxypropyl)-1-propylsulfonylpiperidine-4-carboxamide | SMR000032591 | cid_3242381
Type:
Small organic molecule
Emp. Form.:
C15H30N2O4S
Mol. Mass.:
334.475
SMILES:
CCCS(=O)(=O)N1CCC(CC1)C(=O)NCCCOC(C)C
Structure:
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