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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM89734
Substrate
n/a
Meas. Tech.
Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex
EC50
>53000±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule agonists of the CRF-binding protein and CRF-R2 receptor complex PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM89734
Synonyms:
MLS000100123 | N-(3-methyl-2-pyridinyl)-2-phenoxypropanamide | N-(3-methyl-2-pyridyl)-2-phenoxy-propionamide | N-(3-methylpyridin-2-yl)-2-phenoxy-propanamide | N-(3-methylpyridin-2-yl)-2-phenoxypropanamide | SMR000081920 | cid_2977782
Type:
Small organic molecule
Emp. Form.:
C15H16N2O2
Mol. Mass.:
256.2997
SMILES:
CC(Oc1ccccc1)C(=O)Nc1ncccc1C
Structure:
Search PDB for entries with ligand similarity: