Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM91501
Substrate
n/a
Meas. Tech.
Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA)
EC50
>103971±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM91501
Synonyms:
2,2-dimethyl-N-(2,2,2-trichloro-1-pyrimidin-4-ylsulfanylethyl)propanamide | 2,2-dimethyl-N-[2,2,2-trichloro-1-(4-pyrimidinylthio)ethyl]propanamide | 2,2-dimethyl-N-[2,2,2-trichloro-1-(4-pyrimidylthio)ethyl]propionamide | 2,2-dimethyl-N-[2,2,2-tris(chloranyl)-1-pyrimidin-4-ylsulfanyl-ethyl]propanamide | MLS000717048 | SMR000280015 | cid_3090179
Type:
Small organic molecule
Emp. Form.:
C11H14Cl3N3OS
Mol. Mass.:
342.672
SMILES:
CC(C)(C)C(=O)NC(Sc1ccncn1)C(Cl)(Cl)Cl
Structure:
Search PDB for entries with ligand similarity: