Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM46573
Substrate
n/a
Meas. Tech.
Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA)
EC50
36416±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM46573
Synonyms:
5-nitro-2-thiophenecarboxylic acid [2-(1H-indol-3-yl)-2-oxoethyl] ester | 5-nitrothiophene-2-carboxylic acid [2-(1H-indol-3-yl)-2-keto-ethyl] ester | MLS000417203 | SMR000264453 | [2-(1H-indol-3-yl)-2-oxidanylidene-ethyl] 5-nitrothiophene-2-carboxylate | [2-(1H-indol-3-yl)-2-oxoethyl] 5-nitrothiophene-2-carboxylate | cid_2472581
Type:
Small organic molecule
Emp. Form.:
C15H10N2O5S
Mol. Mass.:
330.315
SMILES:
[O-][N+](=O)c1ccc(s1)C(=O)OCC(=O)c1c[nH]c2ccccc12
Structure:
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