Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM76596
Substrate
n/a
Meas. Tech.
Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA)
EC50
>103905±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM76596
Synonyms:
5-nitro-2-thiophenecarboxylic acid [2-oxo-2-(4-sulfamoylanilino)ethyl] ester | 5-nitrothiophene-2-carboxylic acid [2-keto-2-(4-sulfamoylanilino)ethyl] ester | MLS001002314 | SMR000368835 | [2-oxidanylidene-2-[(4-sulfamoylphenyl)amino]ethyl] 5-nitrothiophene-2-carboxylate | [2-oxo-2-(4-sulfamoylanilino)ethyl] 5-nitrothiophene-2-carboxylate | cid_2424610
Type:
Small organic molecule
Emp. Form.:
C13H11N3O7S2
Mol. Mass.:
385.372
SMILES:
NS(=O)(=O)c1ccc(NC(=O)COC(=O)c2ccc(s2)[N+]([O-])=O)cc1
Structure:
Search PDB for entries with ligand similarity: