Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM76790
Substrate
n/a
Meas. Tech.
Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA)
EC50
22917±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM76790
Synonyms:
5-nitro-2-thiophenecarboxylic acid [2-[(2,3-dimethylcyclohexyl)amino]-2-oxoethyl] ester | 5-nitrothiophene-2-carboxylic acid [2-[(2,3-dimethylcyclohexyl)amino]-2-keto-ethyl] ester | MLS002245146 | SMR001308808 | [2-[(2,3-dimethylcyclohexyl)amino]-2-oxidanylidene-ethyl] 5-nitrothiophene-2-carboxylate | [2-[(2,3-dimethylcyclohexyl)amino]-2-oxoethyl] 5-nitrothiophene-2-carboxylate | cid_3977768
Type:
Small organic molecule
Emp. Form.:
C15H20N2O5S
Mol. Mass.:
340.395
SMILES:
CC1CCCC(NC(=O)COC(=O)c2ccc(s2)[N+]([O-])=O)C1C
Structure:
Search PDB for entries with ligand similarity: