Reaction Details Report a problem with these data
Target
Mitochondrial peptide methionine sulfoxide reductase
Ligand
BDBM76791
Substrate
n/a
Meas. Tech.
Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA)
EC50
17416±n/a nM
Citation
 PubChem, PC Absorbance-based biochemical high throughput dose response assay for activators of Methionine sulfoxide reductase A (MsrA) PubChem Bioassay (2012)[AID] 
Target
Name:
Mitochondrial peptide methionine sulfoxide reductase
Synonyms:
MSRA | MSRA protein | MSRA_BOVIN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25822.90
Organism:
Bos taurus
Description:
gi_73586699
Residue:
233
Sequence:
MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK
  
Inhibitor
Name:
BDBM76791
Synonyms:
5-nitro-2-thiophenecarboxylic acid [2-oxo-2-(3-oxo-2,4-dihydroquinoxalin-1-yl)ethyl] ester | 5-nitrothiophene-2-carboxylic acid [2-keto-2-(3-keto-2,4-dihydroquinoxalin-1-yl)ethyl] ester | MLS002245217 | SMR001308872 | [2-oxidanylidene-2-(3-oxidanylidene-2,4-dihydroquinoxalin-1-yl)ethyl] 5-nitrothiophene-2-carboxylate | [2-oxo-2-(3-oxo-2,4-dihydroquinoxalin-1-yl)ethyl] 5-nitrothiophene-2-carboxylate | cid_2403219
Type:
Small organic molecule
Emp. Form.:
C15H11N3O6S
Mol. Mass.:
361.329
SMILES:
[O-][N+](=O)c1ccc(s1)C(=O)OCC(=O)N1CC(=O)Nc2ccccc12
Structure:
Search PDB for entries with ligand similarity: