Reaction Details Report a problem with these data
Target
Tyrosine-protein phosphatase non-receptor type 5
Ligand
BDBM88728
Substrate
n/a
Meas. Tech.
Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay.
IC50
>80000±n/a nM
Citation
 PubChem, PC Dose response orthogonal assay of uHTS small molecule inhibitors of Striatal-Enriched Phosphatase via a colorimetric intensity assay. PubChem Bioassay (2012)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 5
Synonyms:
PTN5_HUMAN | PTPN5 | Tyrosine-protein phosphatase non-receptor type 5 | Tyrosine-protein phosphatase non-receptor type 5 isoform a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
63510.68
Organism:
Homo sapiens (Human)
Description:
gi_90652859
Residue:
565
Sequence:
MNYEGARSERENHAADDSEGGALDMCCSERLPGLPQPIVMEALDEAEGLQDSQREMPPPPPPSPPSDPAQKPPPRGAGSHSLTVRSSLCLFAASQFLLACGVLWFSGYGHIWSQNATNLVSSLLTLLKQLEPTAWLDSGTWGVPSLLLVFLSVGLVLVTTLVWHLLRTPPEPPTPLPPEDRRQSVSRQPSFTYSEWMEEKIEDDFLDLDPVPETPVFDCVMDIKPEADPTSLTVKSMGLQERRGSNVSLTLDMCTPGCNEEGFGYLMSPREESAREYLLSASRVLQAEELHEKALDPFLLQAEFFEIPMNFVDPKEYDIPGLVRKNRYKTILPNPHSRVCLTSPDPDDPLSSYINANYIRGYGGEEKVYIATQGPIVSTVADFWRMVWQEHTPIIVMITNIEEMNEKCTEYWPEEQVAYDGVEITVQKVIHTEDYRLRLISLKSGTEERGLKHYWFTSWPDQKTPDRAPPLLHLVREVEEAAQQEGPHCAPIIVHCSAGIGRTGCFIATSICCQQLRQEGVVDILKTTCQLRQDRGGMIQTCEQYQFVHHVMSLYEKQLSHQSPE
  
Inhibitor
Name:
BDBM88728
Synonyms:
1-naphthalenecarboxylic acid [(Z)-[amino-(3-nitrophenyl)methylidene]amino] ester | MLS000577491 | N'-(1-naphthoyloxy)-3-nitrobenzenecarboximidamide | SMR000185481 | [(Z)-[amino-(3-nitrophenyl)methylidene]amino] naphthalene-1-carboxylate | [(Z)-[azanyl-(3-nitrophenyl)methylidene]amino] naphthalene-1-carboxylate | cid_5338769 | naphthalene-1-carboxylic acid [(Z)-[amino-(3-nitrophenyl)methylene]amino] ester
Type:
Small organic molecule
Emp. Form.:
C18H13N3O4
Mol. Mass.:
335.3135
SMILES:
[O-][N+](=O)c1cccc(c1)C(=[NH2+])[N-]OC(=O)c1cccc2ccccc12
Structure:
Search PDB for entries with ligand similarity: