Reaction Details Report a problem with these data
Target
Alpha-(1,3)-fucosyltransferase 7
Ligand
BDBM50100861
Substrate
n/a
Meas. Tech.
SPA Assay
pH
7.3±0
Temperature
295.15±0 K
IC50
137000±45000 nM
Citation
 Niu, X; Fan, X; Sun, J; Ting, P; Narula, S; Lundell, D Inhibition of fucosyltransferase VII by gallic acid and its derivatives. Arch Biochem Biophys 425:51-7 (2004) [PubMed]  Article 
Target
Name:
Alpha-(1,3)-fucosyltransferase 7
Synonyms:
Alpha-(1,3)-fucosyltransferase VII | FUT7 | FUT7_HUMAN | Fucosyltransferase VII | Fuct VII
Type:
n/a
Mol. Mass.:
39259.56
Organism:
Homo sapiens (Human)
Description:
Q11130
Residue:
342
Sequence:
MNNAGHGPTRRLRGLGVLAGVALLAALWLLWLLGSAPRGTPAPQPTITILVWHWPFTDQPPELPSDTCTRYGIARCHLSANRSLLASADAVVFHHRELQTRRSHLPLAQRPRGQPWVWASMESPSHTHGLSHLRGIFNWVLSYRRDSDIFVPYGRLEPHWGPSPPLPAKSRVAAWVVSNFQERQLRARLYRQLAPHLRVDVFGRANGRPLCASCLVPTVAQYRFYLSFENSQHRDYITEKFWRNALVAGTVPVVLGPPRATYEAFVPADAFVHVDDFGSARELAAFLTGMNESRYQRFFAWRDRLRVRLFTDWRERFCAICDRYPHLPRSQVYEDLEGWFQA
  
Inhibitor
Name:
BDBM50100861
Synonyms:
3,4-Dihydroxybenzoate, VIII | 3,4-dihydroxybenzoic acid | 4,5-Dihydroxybenzoic acid | 4-Carboxy-1,2-dihydroxybenzene | CHEMBL37537 | Protocatechuic acid | Protocatechuic acid (M1) | Protocatehuic acid | cid_72
Type:
Small organic molecule
Emp. Form.:
C7H6O4
Mol. Mass.:
154.1201
SMILES:
OC(=O)c1ccc(O)c(O)c1
Structure:
Search PDB for entries with ligand similarity: