Reaction Details Report a problem with these data
Target
Acid phosphatase
Ligand
BDBM92478
Substrate
n/a
Meas. Tech.
Inhibitor Screening Assay
Ki
3.42e+5± 5.0e+4 nM
Citation
 McRae, S; Pagliai, FA; Mohapatra, NP; Gener, A; Mahmou, AS; Gunn, JS; Lorca, GL; Gonzalez, CF Inhibition of AcpA phosphatase activity with ascorbate attenuates Francisella tularensis intramacrophage survival. J Biol Chem 285:5171-7 (2010) [PubMed]  Article 
Target
Name:
Acid phosphatase
Synonyms:
Acid phosphatase (acpA) | Acid phosphatase (acpB) | Acid phosphatase (acpC)
Type:
Enzyme
Mol. Mass.:
22350.38
Organism:
Francisella tularensis
Description:
Q5NIC0
Residue:
194
Sequence:
MTQQQVISYYESTAHENEVELILARAKKIIQAQQSLQGNAIVLDIDETALNHYYSLKLAGFPQGENHTIWNELLSRTDAYPIKATLDFYLYCLTSGLKVFFISARFAQYLESTKQALRNAGYVNFEDVFVFPENIEQYNSKDFKNFKAERRAYIESLGYKILISIGDQSSDLLGGYTLYTLQLPNYLYGENSRF
  
Inhibitor
Name:
BDBM92478
Synonyms:
Atracurium besylate | CHEMBL1360
Type:
Molecule
Emp. Form.:
C53H72N2O12
Mol. Mass.:
929.1439
SMILES:
COc1ccc(CC2c3cc(OC)c(OC)cc3CC[N+]2(C)CCC(=O)OCCCCCOC(=O)CC[N+]2(C)CCc3cc(OC)c(OC)cc3C2Cc2ccc(OC)c(OC)c2)cc1OC
Structure:
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