Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM54724
Substrate
n/a
IC50
18676±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM54724
Synonyms:
1-anilino-3-phenyl-1H-pyrrole-2,5-dione | 1-anilino-3-phenyl-3-pyrroline-2,5-quinone | 1-anilino-3-phenylpyrrole-2,5-dione | 3-phenyl-1-phenylazanyl-pyrrole-2,5-dione | MLS000540410 | SMR000125668 | cid_1484338
Type:
Small organic molecule
Emp. Form.:
C16H12N2O2
Mol. Mass.:
264.2787
SMILES:
O=C1C=C(C(=O)N1Nc1ccccc1)c1ccccc1 |c:2|
Structure:
Search PDB for entries with ligand similarity: