Reaction Details Report a problem with these data
Target
Beta-lactamase
Ligand
BDBM61923
Substrate
n/a
IC50
23425±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM61923
Synonyms:
KSC-6-110 | KUC103884N | N-(3-keto-2-phenyl-1,2-benzothiazol-5-yl)acetamide | N-(3-oxidanylidene-2-phenyl-1,2-benzothiazol-5-yl)ethanamide | N-(3-oxo-2-phenyl-1,2-benzothiazol-5-yl)acetamide | cid_44593869
Type:
Small organic molecule
Emp. Form.:
C15H12N2O2S
Mol. Mass.:
284.333
SMILES:
CC(=O)Nc1ccc2sn(-c3ccccc3)c(=O)c2c1
Structure:
Search PDB for entries with ligand similarity: