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Target
Receptor-interacting serine/threonine-protein kinase 2
Ligand
BDBM71504
Substrate
n/a
IC50
1116±n/a nM
Citation
 PubChem, PC Fluorescence-based cell-based high throughput dose response assay for inhibitors of the interaction of nucleotide-binding oligomerization domain containing 2 (NOD2) and the receptor-interacting serine-threonine kinase 2 (RIPK2) PubChem Bioassay (2012)[AID] 
Target
Name:
Receptor-interacting serine/threonine-protein kinase 2
Synonyms:
CARDIAK | RICK | RIP2 | RIPK2 | RIPK2_HUMAN | Serine/threonine-protein kinase RIPK2 | Tyrosine-protein kinase RIPK2 | receptor-interacting serine/threonine-protein kinase 2
Type:
Protein
Mol. Mass.:
61201.30
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
540
Sequence:
MNGEAICSALPTIPYHKLADLRYLSRGASGTVSSARHADWRVQVAVKHLHIHTPLLDSERKDVLREAEILHKARFSYILPILGICNEPEFLGIVTEYMPNGSLNELLHRKTEYPDVAWPLRFRILHEIALGVNYLHNMTPPLLHHDLKTQNILLDNEFHVKIADFGLSKWRMMSLSQSRSSKSAPEGGTIIYMPPENYEPGQKSRASIKHDIYSYAVITWEVLSRKQPFEDVTNPLQIMYSVSQGHRPVINEESLPYDIPHRARMISLIESGWAQNPDERPSFLKCLIELEPVLRTFEEITFLEAVIQLKKTKLQSVSSAIHLCDKKKMELSLNIPVNHGPQEESCGSSQLHENSGSPETSRSLPAPQDNDFLSRKAQDCYFMKLHHCPGNHSWDSTISGSQRAAFCDHKTTPCSSAIINPLSTAGNSERLQPGIAQQWIQSKREDIVNQMTEACLNQSLDALLSRDLIMKEDYELVSTKPTRTSKVRQLLDTTDIQGEEFAKVIVQKLKDNKQMGLQPYPEILVVSRSPSLNLLQNKSM
  
Inhibitor
Name:
BDBM71504
Synonyms:
1-(5-chlorobenzofurazan-4-yl)sulfonylisonipecotic acid ethyl ester | 1-[(5-chloro-2,1,3-benzoxadiazol-4-yl)sulfonyl]-4-piperidinecarboxylic acid ethyl ester | MLS001098320 | SMR000657651 | cid_2813585 | ethyl 1-[(5-chloranyl-2,1,3-benzoxadiazol-4-yl)sulfonyl]piperidine-4-carboxylate | ethyl 1-[(5-chloro-2,1,3-benzoxadiazol-4-yl)sulfonyl]-4-piperidinecarboxylate | ethyl 1-[(5-chloro-2,1,3-benzoxadiazol-4-yl)sulfonyl]piperidine-4-carboxylate
Type:
Small organic molecule
Emp. Form.:
C14H16ClN3O5S
Mol. Mass.:
373.812
SMILES:
CCOC(=O)C1CCN(CC1)S(=O)(=O)c1c(Cl)ccc2nonc12
Structure:
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