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Target
Protein Wnt-3a
Ligand
BDBM89317
Substrate
n/a
IC50
449±n/a nM
Citation
 PubChem, PC Dose response validation of uHTS Gli-SUFU antagonist hits in a Wnt3a luminescent reporter assay PubChem Bioassay (2012)[AID] 
Target
Name:
Protein Wnt-3a
Synonyms:
WNT3A_MOUSE | Wnt-3a | Wnt3a | protein Wnt-3a precursor
Type:
PROTEIN
Mol. Mass.:
39269.29
Organism:
Mus musculus
Description:
ChEMBL_813156
Residue:
352
Sequence:
MAPLGYLLVLCSLKQALGSYPIWWSLAVGPQYSSLSTQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGVKAGIQECQHQFRGRRWNCTTVSNSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGSAAICGCSSRLQGSPGEGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRTIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARTERRREKCHCVFHWCCYVSCQECTRVYDVHTCK
  
Inhibitor
Name:
BDBM89317
Synonyms:
3-(2-amino-5-bromo-phenyl)-1H-quinoxalin-2-one | 3-(2-amino-5-bromophenyl)-1H-quinoxalin-2-one | 3-(2-azanyl-5-bromanyl-phenyl)-1H-quinoxalin-2-one | MLS000714519 | SMR000274498 | cid_754594
Type:
Small organic molecule
Emp. Form.:
C14H10BrN3O
Mol. Mass.:
316.153
SMILES:
Nc1ccc(Br)cc1-c1nc2ccccc2[nH]c1=O
Structure:
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