Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93750
Substrate
n/a
IC50
>64000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93750
Synonyms:
4-{5-[3-(2,4-Dichloro-phenoxy)-propyl]-[1,2,4]oxadiazol-3-yl}-pyridine | 5-[3-(2,4-dichlorophenoxy)propyl]-3-(4-pyridyl)-1,2,4-oxadiazole | 5-[3-(2,4-dichlorophenoxy)propyl]-3-pyridin-4-yl-1,2,4-oxadiazole | 5-[3-[2,4-bis(chloranyl)phenoxy]propyl]-3-pyridin-4-yl-1,2,4-oxadiazole | MLS000528821 | SMR000121296 | cid_1971455
Type:
Small organic molecule
Emp. Form.:
C16H13Cl2N3O2
Mol. Mass.:
350.199
SMILES:
Clc1ccc(OCCCc2nc(no2)-c2ccncc2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: