Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93938
Substrate
n/a
IC50
49900±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93938
Synonyms:
MLS003121441 | N-[2-ethyl-8-[4-(trifluoromethyl)benzyl]oxy-imidazo[1,2-a]pyridin-3-yl]-N-methyl-isonicotinamide | N-[2-ethyl-8-[[4-(trifluoromethyl)phenyl]methoxy]-3-imidazo[1,2-a]pyridinyl]-N-methyl-4-pyridinecarboxamide | N-[2-ethyl-8-[[4-(trifluoromethyl)phenyl]methoxy]imidazo[1,2-a]pyridin-3-yl]-N-methyl-pyridine-4-carboxamide | N-[2-ethyl-8-[[4-(trifluoromethyl)phenyl]methoxy]imidazo[1,2-a]pyridin-3-yl]-N-methylpyridine-4-carboxamide | SMR001284219 | cid_46948337
Type:
Small organic molecule
Emp. Form.:
C24H21F3N4O2
Mol. Mass.:
454.4443
SMILES:
CCc1nc2c(OCc3ccc(cc3)C(F)(F)F)cccn2c1N(C)C(=O)c1ccncc1
Structure:
Search PDB for entries with ligand similarity: