Reaction Details
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Report a problem with these dataTarget
Heat shock protein hsp-16.2
Ligand
BDBM49493
Substrate
n/a
IC50
44520±n/a nM
Citation
PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
Inhibitor
Name:
BDBM49493
Synonyms:
2-(5-bromanylthiophen-2-yl)imidazo[1,2-a]pyridine | 2-(5-bromo-2-thienyl)imidazo[1,2-a]pyridine | 2-(5-bromo-2-thiophenyl)imidazo[1,2-a]pyridine | 2-(5-bromothiophen-2-yl)imidazo[1,2-a]pyridine | MLS000544361 | SMR000162876 | cid_711734
Type:
Small organic molecule
Emp. Form.:
C11H7BrN2S
Mol. Mass.:
279.156
SMILES:
Brc1ccc(s1)-c1cn2ccccc2n1
Structure:
