Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM93818
Substrate
n/a
IC50
>64000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM93818
Synonyms:
(E)-3-(4-bromo-2-fluoro-anilino)-1-(2-furyl)prop-2-en-1-one | (E)-3-(4-bromo-2-fluoroanilino)-1-(2-furanyl)-2-propen-1-one | (E)-3-(4-bromo-2-fluoroanilino)-1-(furan-2-yl)prop-2-en-1-one | (E)-3-[(4-bromanyl-2-fluoranyl-phenyl)amino]-1-(furan-2-yl)prop-2-en-1-one | 3-[(4-bromo-2-fluorophenyl)amino]-1-(2-furyl)-2-propen-1-one | MLS000662279 | SMR000293180 | cid_2197085
Type:
Small organic molecule
Emp. Form.:
C13H9BrFNO2
Mol. Mass.:
310.118
SMILES:
Fc1cc(Br)ccc1N=CCC(=O)c1ccco1 |w:8.8|
Structure:
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