Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM69561
Substrate
n/a
IC50
>64000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM69561
Synonyms:
MLS000861114 | N-(tert-butyl)-5-(4-chlorophenyl)-6H-1,3,4-thiadiazin-2-amine | N-tert-butyl-5-(4-chlorophenyl)-6H-1,3,4-thiadiazin-2-amine | SMR000459898 | cid_696773 | tert-butyl-[5-(4-chlorophenyl)-6H-1,3,4-thiadiazin-2-yl]amine
Type:
Small organic molecule
Emp. Form.:
C13H16ClN3S
Mol. Mass.:
281.804
SMILES:
CC(C)(C)NC1=NN=C(CS1)c1ccc(Cl)cc1 |c:7,t:5|
Structure:
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