Reaction Details Report a problem with these data
Target
Heat shock protein hsp-16.2
Ligand
BDBM49964
Substrate
n/a
IC50
>64000±n/a nM
Citation
 PubChem, PC Dose Response Confirmation of SKN-1 Inhibitor hits via a heat-shock counterscreen assay PubChem Bioassay (2012)[AID] 
Target
Name:
Heat shock protein hsp-16.2
Synonyms:
HSP12_CAEEL | Protein HSP-16.2 | hsp-16 | hsp-16.2 | hsp16-2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
16239.18
Organism:
Caenorhabditis elegans
Description:
gi_373219859
Residue:
145
Sequence:
MSLYHYFRPAQRSVFGDLMRDMALMERQFAPVCRISPSESSEIVNNDQKFAINLNVSQFKPEDLKINLDGRTLSIQGEQELKTDHGYSKKSFSRVILLPEDVDVGAVASNLSEDGKLSIEAPKKEAVQGRSIPIQQAIVEEKSAE
  
Inhibitor
Name:
BDBM49964
Synonyms:
MLS000771256 | N-[3-chloro-4-(difluoromethoxy)phenyl]-2-pyridinecarboxamide | N-[3-chloro-4-(difluoromethoxy)phenyl]picolinamide | N-[3-chloro-4-(difluoromethoxy)phenyl]pyridine-2-carboxamide | N-[4-[bis(fluoranyl)methoxy]-3-chloranyl-phenyl]pyridine-2-carboxamide | SMR000376144 | cid_2579010
Type:
Small organic molecule
Emp. Form.:
C13H9ClF2N2O2
Mol. Mass.:
298.673
SMILES:
FC(F)Oc1ccc(NC(=O)c2ccccn2)cc1Cl
Structure:
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