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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM72369
Substrate
n/a
IC50
5420±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM72369
Synonyms:
5-nitro-2-(phenylthio)pyridine | 5-nitro-2-phenylsulfanyl-pyridine | 5-nitro-2-phenylsulfanylpyridine | MLS000676831 | SMR000271839 | cid_699570
Type:
Small organic molecule
Emp. Form.:
C11H8N2O2S
Mol. Mass.:
232.258
SMILES:
[O-][N+](=O)c1ccc(Sc2ccccc2)nc1
Structure:
Search PDB for entries with ligand similarity: