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Target
Corticotropin-releasing factor-binding protein
Ligand
BDBM89737
Substrate
n/a
IC50
2160±n/a nM
Citation
 PubChem, PC Dose Response confirmation of uHTS hits for small molecule antagonists of the CRF-binding protein and CRF-R2 receptor complex in 384 well format PubChem Bioassay (2012)[AID] 
Target
Name:
Corticotropin-releasing factor-binding protein
Synonyms:
CRFBP | CRHBP | CRHBP_HUMAN | corticotropin releasing factor-binding protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36143.95
Organism:
Homo sapiens (Human)
Description:
P24387
Residue:
322
Sequence:
MSPNFKLQCHFILIFLTALRGESRYLELREAADYDPFLLFSANLKRELAGEQPYRRALRCLDMLSLQGQFTFTADRPQLHCAAFFISEPEEFITIHYDQVSIDCQGGDFLKVFDGWILKGEKFPSSQDHPLPSAERYIDFCESGLSRRSIRSSQNVAMIFFRVHEPGNGFTLTIKTDPNLFPCNVISQTPNGKFTLVVPHQHRNCSFSIIYPVVIKISDLTLGHVNGLQLKKSSAGCEGIGDFVELLGGTGLDPSKMTPLADLCYPFHGPAQMKVGCDNTVVRMVSSGKHVNRVTFEYRQLEPYELENPNGNSIGEFCLSGL
  
Inhibitor
Name:
BDBM89737
Synonyms:
1-(5-chloranyl-2-ethoxy-phenyl)sulfonylbenzotriazole | 1-(5-chloro-2-ethoxy-phenyl)sulfonylbenzotriazole | 1-(5-chloro-2-ethoxyphenyl)sulfonylbenzotriazole | 1-[(5-chloro-2-ethoxyphenyl)sulfonyl]-1H-1,2,3-benzotriazole | MLS000063730 | SMR000075494 | cid_976825
Type:
Small organic molecule
Emp. Form.:
C14H12ClN3O3S
Mol. Mass.:
337.781
SMILES:
CCOc1ccc(Cl)cc1S(=O)(=O)n1nnc2ccccc12
Structure:
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