Reaction Details Report a problem with these data
Target
Perilipin-1
Ligand
BDBM94527
Substrate
n/a
IC50
1933±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) PubChem Bioassay (2012)[AID] 
Target
Name:
Perilipin-1
Synonyms:
PERI | PLIN | PLIN1 | PLIN1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55988.69
Organism:
Homo sapiens (Human)
Description:
gi_223718203
Residue:
522
Sequence:
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDTEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
  
Inhibitor
Name:
BDBM94527
Synonyms:
2-(1-benzofuran-2-yl)-N-tert-butyl-2-[3-(furan-2-yl)-2-oxidanylidene-quinoxalin-1-yl]ethanamide | 2-(1-benzofuran-2-yl)-N-tert-butyl-2-[3-(furan-2-yl)-2-oxoquinoxalin-1-yl]acetamide | 2-(2-benzofuranyl)-N-tert-butyl-2-[3-(2-furanyl)-2-oxo-1-quinoxalinyl]acetamide | 2-(benzofuran-2-yl)-N-tert-butyl-2-[3-(2-furyl)-2-keto-quinoxalin-1-yl]acetamide | MLS003674212 | SMR002353680 | cid_53383337
Type:
Small organic molecule
Emp. Form.:
C26H23N3O4
Mol. Mass.:
441.4785
SMILES:
CC(C)(C)NC(=O)C(c1cc2ccccc2o1)n1c2ccccc2nc(-c2ccco2)c1=O
Structure:
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