Reaction Details Report a problem with these data
Target
Perilipin-1
Ligand
BDBM94551
Substrate
n/a
IC50
2014±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) PubChem Bioassay (2012)[AID] 
Target
Name:
Perilipin-1
Synonyms:
PERI | PLIN | PLIN1 | PLIN1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55988.69
Organism:
Homo sapiens (Human)
Description:
gi_223718203
Residue:
522
Sequence:
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDTEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
  
Inhibitor
Name:
BDBM94551
Synonyms:
2-[3-(2-furanyl)-2-oxo-1-quinoxalinyl]-2-(1-naphthalenyl)-N-pentylacetamide | 2-[3-(furan-2-yl)-2-oxidanylidene-quinoxalin-1-yl]-2-naphthalen-1-yl-N-pentyl-ethanamide | 2-[3-(furan-2-yl)-2-oxoquinoxalin-1-yl]-2-naphthalen-1-yl-N-pentylacetamide | MLS003674167 | N-amyl-2-[3-(2-furyl)-2-keto-quinoxalin-1-yl]-2-(1-naphthyl)acetamide | SMR002353635 | cid_53383149
Type:
Small organic molecule
Emp. Form.:
C29H27N3O3
Mol. Mass.:
465.543
SMILES:
CCCCCNC(=O)C(c1cccc2ccccc12)n1c2ccccc2nc(-c2ccco2)c1=O
Structure:
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