Reaction Details Report a problem with these data
Target
Perilipin-1
Ligand
BDBM83788
Substrate
n/a
IC50
1820±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-5 (MLDP; PLIN5) PubChem Bioassay (2012)[AID] 
Target
Name:
Perilipin-1
Synonyms:
PERI | PLIN | PLIN1 | PLIN1_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55988.69
Organism:
Homo sapiens (Human)
Description:
gi_223718203
Residue:
522
Sequence:
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDTEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
  
Inhibitor
Name:
BDBM83788
Synonyms:
(5Z)-1-benzyl-5-[(E)-3-(2-furyl)prop-2-enylidene]barbituric acid | (5Z)-1-benzyl-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-1,3-diazinane-2,4,6-trione | (5Z)-5-[(E)-3-(2-furanyl)prop-2-enylidene]-1-(phenylmethyl)-1,3-diazinane-2,4,6-trione | (5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-1-(phenylmethyl)-1,3-diazinane-2,4,6-trione | 1-benzyl-5-[3-(2-furyl)-2-propen-1-ylidene]-2,4,6(1H,3H,5H)-pyrimidinetrione | MLS000680483 | SMR000268660 | cid_1908237
Type:
Small organic molecule
Emp. Form.:
C18H14N2O4
Mol. Mass.:
322.3148
SMILES:
O=C1NC(=O)\C(=C\C=C\c2ccco2)C(=O)N1Cc1ccccc1
Structure:
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