Reaction Details
Report a problem with these data
Report a problem with these dataTarget
Sentrin-specific protease 1
Ligand
BDBM94789
Substrate
n/a
IC50
12500±n/a nM
Citation
PubChem, PC Dose response confirmation of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Sentrin-specific protease 1
Synonyms:
SENP1 | SENP1_HUMAN | Sentrin-specific protease 1 (SENP1)
Type:
Protein
Mol. Mass.:
73500.42
Organism:
Homo sapiens (Human)
Description:
Q9P0U3
Residue:
644
Sequence:
MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL
Inhibitor
Name:
BDBM94789
Synonyms:
1-(4-Chloro-phenyl)-3-(4-chloro-phenylamino)-pyrrole-2,5-dione | 1-(4-chlorophenyl)-3-[(4-chlorophenyl)amino]pyrrole-2,5-dione | 3-(4-chloroanilino)-1-(4-chlorophenyl)-3-pyrroline-2,5-quinone | 3-(4-chloroanilino)-1-(4-chlorophenyl)pyrrole-2,5-dione | MLS000591693 | SMR000218656 | cid_949524
Type:
Small organic molecule
Emp. Form.:
C16H10Cl2N2O2
Mol. Mass.:
333.169
SMILES:
Clc1ccc(cc1)N=C1CC(=O)N(C1=O)c1ccc(Cl)cc1 |w:7.7|
Structure:
