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Target
Sentrin-specific protease 1
Ligand
BDBM94837
Substrate
n/a
IC50
9690±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of the catalytic domain of the SUMO protease, SENP1 in a FRET assay PubChem Bioassay (2012)[AID] 
Target
Name:
Sentrin-specific protease 1
Synonyms:
SENP1 | SENP1_HUMAN | Sentrin-specific protease 1 (SENP1)
Type:
Protein
Mol. Mass.:
73500.42
Organism:
Homo sapiens (Human)
Description:
Q9P0U3
Residue:
644
Sequence:
MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTCSTRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYLETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVSTAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNSCASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPHQPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQIEEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEFPEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLMERSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVDFRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNGSDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL
  
Inhibitor
Name:
BDBM94837
Synonyms:
3-[(E)-(3-bromanyl-4-methoxy-phenyl)methylideneamino]-2-sulfanylidene-1,3-thiazolidin-4-one | 3-[(E)-(3-bromo-4-methoxy-benzylidene)amino]-2-thioxo-thiazolidin-4-one | 3-[(E)-(3-bromo-4-methoxyphenyl)methylideneamino]-2-sulfanylidene-1,3-thiazolidin-4-one | 3-[(E)-(3-bromo-4-methoxyphenyl)methylideneamino]-2-sulfanylidene-4-thiazolidinone | MLS001242857 | SMR000841385 | cid_56642851
Type:
Small organic molecule
Emp. Form.:
C11H9BrN2O2S2
Mol. Mass.:
345.235
SMILES:
COc1ccc(C=Nn2c(O)csc2=S)cc1Br |w:7.7|
Structure:
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