Reaction Details Report a problem with these data
Target
Low molecular weight phosphotyrosine protein phosphatase
Ligand
BDBM94885
Substrate
n/a
IC50
6620±n/a nM
Citation
 PubChem, PC Dose response confirmation of small molecule inhibitors of Low Molecular Weight Protein Tyrosine Phosphatase, LMPTP, via a fluorescence intensity assay PubChem Bioassay (2012)[AID] 
Target
Name:
Low molecular weight phosphotyrosine protein phosphatase
Synonyms:
3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:
n/a
Mol. Mass.:
18042.81
Organism:
Homo sapiens (Human)
Description:
P24666
Residue:
158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRGQSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSYDPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
  
Inhibitor
Name:
BDBM94885
Synonyms:
5-(4-methoxyphenyl)-N-[(E)-[5-(4-nitrophenyl)-2-furanyl]methylideneamino]-1,2,4-triazin-3-amine | 5-(4-methoxyphenyl)-N-[(E)-[5-(4-nitrophenyl)furan-2-yl]methylideneamino]-1,2,4-triazin-3-amine | 5-(4-nitrophenyl)-2-furaldehyde [5-(4-methoxyphenyl)-1,2,4-triazin-3-yl]hydrazone | MLS000724516 | SMR000306109 | [5-(4-methoxyphenyl)-1,2,4-triazin-3-yl]-[(E)-[5-(4-nitrophenyl)-2-furyl]methyleneamino]amine | cid_45037809
Type:
Small organic molecule
Emp. Form.:
C21H16N6O4
Mol. Mass.:
416.3895
SMILES:
COc1ccc(cc1)-c1cnnc(n1)\[NH+]=N\[CH-]c1ccc(o1)-c1ccc(cc1)[N+]([O-])=O
Structure:
Search PDB for entries with ligand similarity: