Reaction Details
Report a problem with these data
Report a problem with these dataTarget
Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM80054
Substrate
n/a
IC50
15600±n/a nM
Citation
PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
Inhibitor
Name:
BDBM80054
Synonyms:
2-[[4-[2-[(4-ethoxyphenyl)methylidene]hydrazinyl]-3-nitro-phenyl]sulfonylamino]benzoic acid | 2-[[4-[2-[(4-ethoxyphenyl)methylidene]hydrazinyl]-3-nitrophenyl]sulfonylamino]benzoic acid | 2-[[4-[N'-(4-ethoxybenzylidene)hydrazino]-3-nitro-phenyl]sulfonylamino]benzoic acid | MLS002244890 | SMR001308563 | cid_3874439
Type:
Small organic molecule
Emp. Form.:
C22H20N4O7S
Mol. Mass.:
484.482
SMILES:
CCOc1ccc(CN=Nc2ccc(cc2[N+]([O-])=O)S(=O)(=O)Nc2ccccc2C(O)=O)cc1 |w:9.9|
Structure:
