Reaction Details
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Report a problem with these dataTarget
Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM95127
Substrate
n/a
IC50
15700±n/a nM
Citation
PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
Inhibitor
Name:
BDBM95127
Synonyms:
5-(2,5-dichlorobenzyl)-4-methyl-4-thiazoline-2-thione | 5-[(2,5-dichlorophenyl)methyl]-4-methyl-3H-1,3-thiazole-2-thione | 5-[(2,5-dichlorophenyl)methyl]-4-methyl-3H-thiazole-2-thione | 5-[[2,5-bis(chloranyl)phenyl]methyl]-4-methyl-3H-1,3-thiazole-2-thione | MLS000334618 | SMR000249376 | cid_2554667
Type:
Small organic molecule
Emp. Form.:
C11H9Cl2NS2
Mol. Mass.:
290.232
SMILES:
Cc1nc(S)sc1Cc1cc(Cl)ccc1Cl
Structure:
