Reaction Details
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Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM95133
Substrate
n/a
IC50
16000±n/a nM
Citation
PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
Inhibitor
Name:
BDBM95133
Synonyms:
2-azanylidene-3-[5-[(2-chlorophenyl)methyl]-1,3-thiazol-2-yl]-5-phenyl-1,3-thiazolidin-4-one | 3-[5-(2-chlorobenzyl)thiazol-2-yl]-2-imino-5-phenyl-thiazolidin-4-one | 3-[5-[(2-chlorophenyl)methyl]-1,3-thiazol-2-yl]-2-imino-5-phenyl-1,3-thiazolidin-4-one | 3-[5-[(2-chlorophenyl)methyl]-2-thiazolyl]-2-imino-5-phenyl-4-thiazolidinone | MLS000335826 | SMR000253580 | cid_4880464
Type:
Small organic molecule
Emp. Form.:
C19H14ClN3OS2
Mol. Mass.:
399.917
SMILES:
Clc1ccccc1Cc1cnc(s1)N1C(=N)SC(C1=O)c1ccccc1
Structure:
