Reaction Details
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Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM82868
Substrate
n/a
IC50
15500±n/a nM
Citation
PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
Inhibitor
Name:
BDBM82868
Synonyms:
4-[(2-ketoindol-3-yl)amino]-N-thiazol-2-yl-benzenesulfonamide | 4-[(2-oxidanylideneindol-3-yl)amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide | 4-[(2-oxo-3-indolyl)amino]-N-(2-thiazolyl)benzenesulfonamide | 4-[(2-oxoindol-3-yl)amino]-N-(1,3-thiazol-2-yl)benzenesulfonamide | MLS000738224 | SMR000528585 | cid_280863
Type:
Small organic molecule
Emp. Form.:
C17H12N4O3S2
Mol. Mass.:
384.432
SMILES:
O=C1N=c2ccccc2=C1Nc1ccc(cc1)S(=O)(=O)Nc1nccs1 |c:9,t:2|
Structure:
