Reaction Details
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Probable nicotinate-nucleotide adenylyltransferase
Ligand
BDBM31355
Substrate
n/a
IC50
45400±n/a nM
Citation
PubChem, PC Dose response confirmation of uHTS inhibitor hits from NadD in a Colorimetric assay - Set 2 PubChem Bioassay (2012)[AID] More Info.:
Target
Name:
Probable nicotinate-nucleotide adenylyltransferase
Synonyms:
NADD_STAAN | hypothetical protein SA1422 | nadD
Type:
Enzyme Catalytic Domain
Mol. Mass.:
22100.53
Organism:
Staphylococcus aureus subsp. aureus N315
Description:
gi_15927174
Residue:
189
Sequence:
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH
Inhibitor
Name:
BDBM31355
Synonyms:
2,2-Di-m-tolyl-cyclopropanecarboxylic acid (2-hydroxy-4-nitro-phenyl)-amide | 2,2-bis(3-methylphenyl)-N-(4-nitro-2-oxidanyl-phenyl)cyclopropane-1-carboxamide | MLS000554437 | N-(2-hydroxy-4-nitro-phenyl)-2,2-bis(m-tolyl)cyclopropanecarboxamide | N-(2-hydroxy-4-nitrophenyl)-2,2-bis(3-methylphenyl)-1-cyclopropanecarboxamide | N-(2-hydroxy-4-nitrophenyl)-2,2-bis(3-methylphenyl)cyclopropane-1-carboxamide | SMR000171420 | cid_3105194
Type:
Small organic molecule
Emp. Form.:
C24H22N2O4
Mol. Mass.:
402.4425
SMILES:
Cc1cccc(c1)C1(CC1C(=O)Nc1ccc(cc1O)[N+]([O-])=O)c1cccc(C)c1
Structure:
