Reaction Details Report a problem with these data
Target
ADP-ribosylation factor GTPase-activating protein 1
Ligand
BDBM75956
Substrate
n/a
IC50
78545±n/a nM
Citation
 PubChem, PC Fluorescence polarization-based biochemical high throughput dose response screening assay to identify inhibitors of ADP-ribosylation factor GTPase activating protein 1 (ARFGAP1) PubChem Bioassay (2012)[AID] 
Target
Name:
ADP-ribosylation factor GTPase-activating protein 1
Synonyms:
ARFG1_RAT | Arf1gap | Arfgap1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
45436.38
Organism:
Rattus norvegicus
Description:
gi_21489979
Residue:
415
Sequence:
MASPRTRKVLKEVRAQDENNVCFECGAFNPQWVSVTYGIWICLECSGRHRGLGVHLSFVRSVTMDKWKDIELEKMKAGGNAKFREFLEAQDDYEPSWSLQDKYSSRAAALFRDKVATLAEGKEWSLESSPAQNWTPPQPKTLQFTAHRPAGQPQNVTTSGDKAFEDWLNDDLGSYQGAQENRYVGFGNTVPPQKREDDFLNSAMSSLYSGWSSFTTGASKFASAAKEGATKFGSQASQKASELGHSLNENVLKPAQEKVKEGRIFDDVSSGVSQLASKVQGVGSKGWRDVTTFFSGKAEDTSDRPLEGHSYQNSSGDNSQNSTIDQSFWETFGSAEPPKAKSPSSDSWTCADASTGRRSSDSWDIWGSGSASNNKNSNSDGWESWEGASGEGRAKATKKAAPSTAADEGWDNQNW
  
Inhibitor
Name:
BDBM75956
Synonyms:
3-Methyl-benzofuran-2-carboxylic acid (4-tetrazol-1-yl-phenyl)-amide | 3-methyl-N-[4-(1,2,3,4-tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide | 3-methyl-N-[4-(1-tetrazolyl)phenyl]-2-benzofurancarboxamide | 3-methyl-N-[4-(tetrazol-1-yl)phenyl]-1-benzofuran-2-carboxamide | 3-methyl-N-[4-(tetrazol-1-yl)phenyl]coumarilamide | MLS000068640 | SMR000003826 | cid_648856
Type:
Small organic molecule
Emp. Form.:
C17H13N5O2
Mol. Mass.:
319.3174
SMILES:
Cc1c(oc2ccccc12)C(=O)Nc1ccc(cc1)-n1cnnn1
Structure:
Search PDB for entries with ligand similarity: